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Investigating the effects of two novel 4-MMPB analogs as potent lipoxygenase inhibitors for prostate cancer treatment

BACKGROUND: Lipoxygenases are one of the critical signaling mediators which can be targeted for human prostate cancer (PC) therapy. In this study, 4-methyl-2-(4-methylpiperazinyl)pyrimido[4,5-b]benzothiazine (4-MMPB) and its two analogs, 4-propyl-2-(4-methylpiperazinyl)pyrimido[4,5-b]benzothiazine (...

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Detalles Bibliográficos
Autores principales:	Iranpour, Sonia, Al-Mosawi, Aseel Kamil Mohammed, Bahrami, Ahmad Reza, Sadeghian, Hamid, Matin, Maryam M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097893/ https://www.ncbi.nlm.nih.gov/pubmed/33947474 http://dx.doi.org/10.1186/s40709-021-00141-w

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