Enhancement of doxorubicin anti-cancer activity by vascular targeting using IsoDGR/cytokine-coated nanogold

BACKGROUND: Gold nanospheres tagged with peptides containing isoDGR (isoAsp-Gly-Arg), an αvβ3 integrin binding motif, represent efficient carriers for delivering pro-inflammatory cytokines to the tumor vasculature. We prepared bi- or trifunctional nanoparticles bearing tumor necrosis factor-α (TNF)...

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Detalles Bibliográficos
Autores principales: Corti, Angelo, Sacchi, Angelina, Gasparri, Anna Maria, Monieri, Matteo, Anderluzzi, Giulia, Colombo, Barbara, Gori, Alessandro, Mondino, Anna, Curnis, Flavio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097910/
https://www.ncbi.nlm.nih.gov/pubmed/33952242
http://dx.doi.org/10.1186/s12951-021-00871-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097910/
https://www.ncbi.nlm.nih.gov/pubmed/33952242
http://dx.doi.org/10.1186/s12951-021-00871-y

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