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Angiotensin II upregulates RANKL/NFATC1 expression in synovial cells from patients with rheumatoid arthritis through the ERK1/2 and JNK pathways
BACKGROUND: Angiotensin II (Ang II) is associated with rheumatoid arthritis (RA) development. The present study investigated the impact of Ang II on the expression of receptor activator of nuclear factor-κB ligand (RANKL), as well as of nuclear factor of activated T cells cytoplasmic 1 (NFATC1) in R...
Autores principales: | Zhao, Zhiping, Zhang, Yongtao, Wang, Changyao, Wang, Xiangyu, Wang, Yingzhen, Zhang, Haining |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097914/ https://www.ncbi.nlm.nih.gov/pubmed/33952303 http://dx.doi.org/10.1186/s13018-021-02451-0 |
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