Temporal gene regulation by p53 is associated with the rotational setting of its binding sites in nucleosomes

The tumor suppressor protein p53 is a DNA-binding transcription factor (TF) that, once activated, coordinates the expression of thousands of target genes. Increased p53 binding to gene promoters occurs shortly after p53 activation. Intriguingly, gene transcription exhibits differential kinetics with...

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Detalles Bibliográficos
Autores principales: Freewoman, Julia M., Snape, Rajiv, Cui, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8098069/
https://www.ncbi.nlm.nih.gov/pubmed/33764853
http://dx.doi.org/10.1080/15384101.2021.1904554

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8098069/
https://www.ncbi.nlm.nih.gov/pubmed/33764853
http://dx.doi.org/10.1080/15384101.2021.1904554

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