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JAK1 selective inhibitors for the treatment of spondyloarthropathies
As our understanding of the pathogenesis of SpA improves, focus has turned to the role janus kinase (JAK)-mediated signal transduction and inhibiting its actions as a therapeutic mechanism. Small molecule inhibitors of JAK exist, with variable selectivity for the different JAK isoforms. Less selecti...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8098108/ https://www.ncbi.nlm.nih.gov/pubmed/33950224 http://dx.doi.org/10.1093/rheumatology/keaa815 |