Transethnic analysis of the human leukocyte antigen region for ulcerative colitis reveals not only shared but also ethnicity-specific disease associations

Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the gut. Genetic association studies have identified the highly variable human leukocyte antigen (HLA) region as the strongest susceptibility locus for IBD and specifically DRB1(*)01:03 as a determining factor for ulcerative colit...

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Detalles Bibliográficos
Autores principales: Degenhardt, Frauke, Mayr, Gabriele, Wendorff, Mareike, Boucher, Gabrielle, Ellinghaus, Eva, Ellinghaus, David, ElAbd, Hesham, Rosati, Elisa, Hübenthal, Matthias, Juzenas, Simonas, Abedian, Shifteh, Vahedi, Homayon, Thelma, B K, Yang, Suk-Kyun, Ye, Byong Duk, Cheon, Jae Hee, Datta, Lisa Wu, Daryani, Naser Ebrahim, Ellul, Pierre, Esaki, Motohiro, Fuyuno, Yuta, McGovern, Dermot P B, Haritunians, Talin, Hong, Myhunghee, Juyal, Garima, Jung, Eun Suk, Kubo, Michiaki, Kugathasan, Subra, Lenz, Tobias L, Leslie, Stephen, Malekzadeh, Reza, Midha, Vandana, Motyer, Allan, Ng, Siew C, Okou, David T, Raychaudhuri, Soumya, Schembri, John, Schreiber, Stefan, Song, Kyuyoung, Sood, Ajit, Takahashi, Atsushi, Torres, Esther A, Umeno, Junji, Alizadeh, Behrooz Z, Weersma, Rinse K, Wong, Sunny H, Yamazaki, Keiko, Karlsen, Tom H, Rioux, John D, Brant, Steven R, Franke, Andre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
General Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8098114/
https://www.ncbi.nlm.nih.gov/pubmed/33555323
http://dx.doi.org/10.1093/hmg/ddab017

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