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R-loops at centromeric chromatin contribute to defects in kinetochore integrity and chromosomal instability in budding yeast
R-loops, the byproduct of DNA–RNA hybridization and the displaced single-stranded DNA (ssDNA), have been identified in bacteria, yeasts, and other eukaryotic organisms. The persistent presence of R-loops contributes to defects in DNA replication and repair, gene expression, and genomic integrity. R-...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8098821/ https://www.ncbi.nlm.nih.gov/pubmed/33147102 http://dx.doi.org/10.1091/mbc.E20-06-0379 |