Myosin II isoforms promote internalization of spatially distinct clathrin-independent endocytosis cargoes through modulation of cortical tension downstream of ROCK2

Although the actomyosin cytoskeleton has been implicated in clathrin-mediated endocytosis, a clear requirement for actomyosin in clathrin-independent endocytosis (CIE) has not been demonstrated. We discovered that the Rho-associated kinase ROCK2 is required for CIE of MHCI and CD59 through promotion...

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Detalles Bibliográficos
Autores principales: Wayt, Jessica, Cartagena-Rivera, Alexander, Dutta, Dipannita, Donaldson, Julie G., Waterman, Clare M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8098828/
https://www.ncbi.nlm.nih.gov/pubmed/33326251
http://dx.doi.org/10.1091/mbc.E20-07-0480

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