Integrin-linked kinase tunes cell–cell and cell-matrix adhesions to regulate the switch between apoptosis and EMT downstream of TGFβ1

Epithelial-mesenchymal transition (EMT) is a morphogenetic process that endows epithelial cells with migratory and invasive potential. Mechanical and chemical signals from the tumor microenvironment can activate the EMT program, thereby permitting cancer cells to invade the surrounding stroma and di...

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Detalles Bibliográficos
Autores principales: Kilinc, Ayse Nihan, Han, Siyang, Barrett, Lena A., Anandasivam, Niroshan, Nelson, Celeste M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8098849/
https://www.ncbi.nlm.nih.gov/pubmed/33405954
http://dx.doi.org/10.1091/mbc.E20-02-0092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8098849/
https://www.ncbi.nlm.nih.gov/pubmed/33405954
http://dx.doi.org/10.1091/mbc.E20-02-0092

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