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Integrin-linked kinase tunes cell–cell and cell-matrix adhesions to regulate the switch between apoptosis and EMT downstream of TGFβ1
Epithelial-mesenchymal transition (EMT) is a morphogenetic process that endows epithelial cells with migratory and invasive potential. Mechanical and chemical signals from the tumor microenvironment can activate the EMT program, thereby permitting cancer cells to invade the surrounding stroma and di...
Autores principales: | Kilinc, Ayse Nihan, Han, Siyang, Barrett, Lena A., Anandasivam, Niroshan, Nelson, Celeste M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8098849/ https://www.ncbi.nlm.nih.gov/pubmed/33405954 http://dx.doi.org/10.1091/mbc.E20-02-0092 |
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