Pannexin 1 mutation found in melanoma tumor reduces phosphorylation, glycosylation, and trafficking of the channel-forming protein

Pannexin 1 (PANX1) is a glycoprotein that forms large pore channels capable of passing ions and metabolites such as ATP for cellular communication. PANX1 has been implicated in many diseases including breast cancer and melanoma, where inhibition or deletion of PANX1 reduced the tumorigenic and metas...

Descripción completa

Detalles Bibliográficos
Autores principales: Nouri-Nejad, Daniel, O’Donnell, Brooke L., Patil, Chetan S., Sanchez-Pupo, Rafael E., Johnston, Danielle, Sayedyahossein, Samar, Jurcic, Kristina, Lau, Rebecca, Gyenis, Laszlo, Litchfield, David W., Jackson, Michael F., Gloor, Gregory B., Penuela, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8098850/
https://www.ncbi.nlm.nih.gov/pubmed/33405952
http://dx.doi.org/10.1091/mbc.E19-10-0585

Ejemplares similares

Ejemplares similares