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Insulin resistance and liver histopathology in metabolically unhealthy subjects do not correlate with the hepatic abundance of NLRP3 inflammasome nor circulating IL-1β levels

INTRODUCTION: Systemic chronic low-grade inflammation has been linked to insulin resistance (IR) and non-alcoholic steatohepatitis (NASH). NOD-like receptor protein 3 (NLRP3) inflammasome and its final product, interleukin (IL)-1β, exert detrimental effects on insulin sensitivity and promote liver i...

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Detalles Bibliográficos
Autores principales:	Quezada, Nicolas, Valencia, Ilse, Torres, Javiera, Maturana, Gregorio, Cerda, Jaime, Arab, Juan Pablo, Fuentes, Juan José, Pinto, Claudio, Turiel, Dannae, Cortés, Victor
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Obesity Studies
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8098916/ https://www.ncbi.nlm.nih.gov/pubmed/33941551 http://dx.doi.org/10.1136/bmjdrc-2020-001975

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