Cargando…

Control Crohn Safe with episodic adalimumab monotherapy as first-line treatment study (CoCroS): study protocol for a randomised controlled trial

INTRODUCTION: Crohn’s disease (CD) is a chronic inflammatory bowel disease with a heterogeneous clinical presentation, relapse rate and treatment response. At present, no markers are available to adequately predict disease course at diagnosis. To prevent overtreatment of patients with a relative mil...

Descripción completa

Detalles Bibliográficos
Autores principales:	Janssen, Laura, Romberg-Camps, Mariëlle, van Bodegraven, Ad, Haans, Jeoffrey, Aquarius, Michèl, Boekema, Paul, Munnecom, Tamara, Brandts, Lloyd, Joore, Manuela, Masclee, Adrian, Jonkers, D, Pierik, M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Gastroenterology and Hepatology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8098960/ https://www.ncbi.nlm.nih.gov/pubmed/33947729 http://dx.doi.org/10.1136/bmjopen-2020-042885

Ejemplares similares

Protocol for a multinational risk-stratified randomised controlled trial in paediatric Crohn’s disease: methotrexate versus azathioprine or adalimumab for maintaining remission in patients at low or high risk for aggressive disease course
por: Harris, Rachel E, et al.
Publicado: (2020)

NSAIDs, statins, low-dose aspirin and PPIs, and the risk of oesophageal adenocarcinoma among patients with Barrett's oesophagus: a population-based case–control study
por: Masclee, Gwen M C, et al.
Publicado: (2015)

Lengthening adalimumab dosing interval in quiescent Crohn’s disease patients: protocol for the pragmatic randomised non-inferiority LADI study
por: Smits, L J T, et al.
Publicado: (2020)

Cohort profile: design and first results of the Dutch IBD Biobank: a prospective, nationwide biobank of patients with inflammatory bowel disease
por: Spekhorst, Lieke M, et al.
Publicado: (2017)

The reproducibility of skeletal muscle signal intensity on routine magnetic resonance imaging in Crohn's disease
por: Spooren, Corinne E.G.M., et al.
Publicado: (2020)

Classic drugs in the time of new drugs: real‐world, long‐term outcomes of thiopurine monotherapy in 1016 patients with inflammatory bowel disease
por: Rezazadeh Ardabili, Ashkan, et al.
Publicado: (2022)

A meta-analysis on randomized controlled trials of treating eosinophilic esophagitis with budesonide
por: Liu, Xiaopei, et al.
Publicado: (2022)

Recompensation factors for patients with decompensated cirrhosis: a multicentre retrospective case–control study
por: Xu, Xiaomei, et al.
Publicado: (2021)

A case–control study comparing the incidence of early symptoms in pancreatic and biliary tract cancer
por: Keane, M G, et al.
Publicado: (2014)

Seminar-case learning model improves clinical teaching: a prospective randomized controlled trial
por: Li, Peiyuan, et al.
Publicado: (2021)

Role of Helicobacter pylori and interleukin 6 -174 gene polymorphism in dyslipidemia: a case–control study
por: Pohjanen, Vesa-Matti, et al.
Publicado: (2016)

Coordinative control of G2/M phase of the cell cycle by non-coding RNAs in hepatocellular carcinoma
por: Shi, Jun, et al.
Publicado: (2018)

Laparoscopic versus open pancreaticoduodenectomy for pancreatic ductal adenocarcinoma: study protocol for a multicentre randomised controlled trial
por: Pan, Shutao, et al.
Publicado: (2022)

Value of an outpatient transition clinic for young people with inflammatory bowel disease: a mixed-methods evaluation
por: Sattoe, Jane N T, et al.
Publicado: (2020)

Antiviral therapy for prevention of hepatocellular carcinoma in chronic hepatitis C: systematic review and meta-analysis of randomised controlled trials
por: Kimer, Nina, et al.
Publicado: (2012)

Randomised controlled trial. Comparison Of iNfliximab and ciclosporin in STeroid Resistant Ulcerative Colitis: Trial design and protocol (CONSTRUCT)
por: Seagrove, Anne C, et al.
Publicado: (2014)

ATTIRE: Albumin To prevenT Infection in chronic liveR failurE: study protocol for an interventional randomised controlled trial
por: China, Louise, et al.
Publicado: (2018)

Protocol for a pilot randomised controlled trial of mindfulness-based cognitive therapy in youth with inflammatory bowel disease and depression
por: Ewais, Tatjana, et al.
Publicado: (2019)

LIFEStyle, Prevention and Risk of Acute PaNcreatitis (LIFESPAN): protocol of a multicentre and multinational observational case–control study
por: Koncz, Balázs, et al.
Publicado: (2020)

Atorvastatin for prevention of disease progression and hospitalisation in liver cirrhosis: protocol for a randomised, double-blind, placebo-controlled trial
por: Kimer, Nina, et al.
Publicado: (2020)

Effects of visual aid on state anxiety, fear and stress level in patients undergoing endoscopy: a randomized controlled trial
por: Khan, Ali Asad, et al.
Publicado: (2023)

Total laparoscopic pancreaticoduodenectomy versus open pancreaticoduodenectomy (TJDBPS01): study protocol for a multicentre, randomised controlled clinical trial
por: Zhang, Hang, et al.
Publicado: (2020)

Inflammatory bowel disease in sub-Saharan Africa: a protocol of a prospective registry with a nested case–control study
por: Katsidzira, Leolin, et al.
Publicado: (2020)

Does knowledge of liver fibrosis affect high-risk drinking behaviour (KLIFAD)? protocol for a feasibility randomised controlled trial
por: Subhani, Mohsan, et al.
Publicado: (2021)

Acceptability and efficacy of the Zemedy app versus a relaxation training and meditation app for IBS: protocol for a randomised controlled trial
por: Hunt, Melissa G, et al.
Publicado: (2022)

Interventions to improve the quality of screening-related colonoscopy: protocol for a systematic review and network meta-analysis of randomised controlled trials
por: Khan, Rishad, et al.
Publicado: (2022)

Viusid, a nutritional supplement, increases survival and reduces disease progression in HCV-related decompensated cirrhosis: a randomised and controlled trial
por: Vilar Gomez, Eduardo, et al.
Publicado: (2011)

Educational virtual reality videos in improving bowel preparation quality and satisfaction of outpatients undergoing colonoscopy: protocol of a randomised controlled trial
por: Zhao, Yi, et al.
Publicado: (2019)

FTACMT study protocol: a multicentre, double-blind, randomised, placebo-controlled trial of faecal microbiota transplantation for autism spectrum disorder
por: Chen, Ye, et al.
Publicado: (2022)

Synergism interaction between genetic polymorphisms in drug metabolizing enzymes and NSAIDs on upper gastrointestinal haemorrhage: a multicenter case-control study
por: Mallah, Narmeen, et al.
Publicado: (2022)

Did an introduction of CONSORT for abstracts guidelines improve reporting quality of randomised controlled trials’ abstracts on Helicobacter pylori infection? Observational study
por: Vrebalov Cindro, Pavle, et al.
Publicado: (2022)

Prospective randomised controlled trial of adults with perianal fistulising Crohn’s disease and optimised therapeutic infliximab levels: PROACTIVE trial study protocol
por: Gu, Bonita, et al.
Publicado: (2021)

Recurrent acute pancreatitis prevention by the elimination of alcohol and cigarette smoking (REAPPEAR): protocol of a randomised controlled trial and a cohort study
por: Ocskay, Klementina, et al.
Publicado: (2022)

Association between medication adherence and disease outcomes in patients with hepatitis B-related cirrhosis: a population-based case–control study
por: Fu, Kuo-Yu, et al.
Publicado: (2022)

Liraglutide efficacy and action in non-alcoholic steatohepatitis (LEAN): study protocol for a phase II multicentre, double-blinded, randomised, controlled trial
por: Armstrong, Matthew J, et al.
Publicado: (2013)

Transjugular intrahepatic portosystemic shunt for the prevention of variceal rebleeding in cirrhotic patients with portal vein thrombosis: study protocol for a randomised controlled trial
por: Qi, Xingshun, et al.
Publicado: (2013)

RITPBC: B-cell depleting therapy (rituximab) as a treatment for fatigue in primary biliary cirrhosis: study protocol for a randomised controlled trial
por: Jopson, Laura, et al.
Publicado: (2015)

Study protocol for a randomised, double-blinded, placebo-controlled, clinical trial of S-ketamine for pain treatment in patients with chronic pancreatitis (RESET trial)
por: Juel, Jacob, et al.
Publicado: (2015)

Protocol for a prospective, controlled, observational study to evaluate the influence of hypoxia on healthy volunteers and patients with inflammatory bowel disease: the Altitude IBD Study
por: Vavricka, Stephan, et al.
Publicado: (2017)

Dose–response association between physical activity and non-alcoholic fatty liver disease: a case–control study in a Chinese population
por: Li, YangFan, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_lskvjvjh6ee2vlbui26o722mhj