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The Immunoproteasome Subunits LMP2, LMP7 and MECL-1 Are Crucial Along the Induction of Cerebral Toxoplasmosis
Cell survival and function critically relies on the fine-tuned balance of protein synthesis and degradation. In the steady state, the standard proteasome is sufficient to maintain this proteostasis. However, upon inflammation, the sharp increase in protein production requires additional mechanisms t...
Autores principales: | French, Timothy, Israel, Nicole, Düsedau, Henning Peter, Tersteegen, Anne, Steffen, Johannes, Cammann, Clemens, Topfstedt, Eylin, Dieterich, Daniela, Schüler, Thomas, Seifert, Ulrike, Dunay, Ildiko Rita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099150/ https://www.ncbi.nlm.nih.gov/pubmed/33968021 http://dx.doi.org/10.3389/fimmu.2021.619465 |
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