SMARCAD1-mediated active replication fork stability maintains genome integrity

The stalled fork protection pathway mediated by breast cancer 1/2 (BRCA1/2) proteins is critical for replication fork stability. However, it is unclear whether additional mechanisms are required to maintain replication fork stability. We describe a hitherto unknown mechanism, by which the SWI/SNF-re...

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Detalles Bibliográficos
Autores principales: Lo, Calvin Shun Yu, van Toorn, Marvin, Gaggioli, Vincent, Paes Dias, Mariana, Zhu, Yifan, Manolika, Eleni Maria, Zhao, Wei, van der Does, Marit, Mukherjee, Chirantani, G. S. C. Souto Gonçalves, João, van Royen, Martin E., French, Pim J., Demmers, Jeroen, Smal, Ihor, Lans, Hannes, Wheeler, David, Jonkers, Jos, Chaudhuri, Arnab Ray, Marteijn, Jurgen A., Taneja, Nitika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099181/
https://www.ncbi.nlm.nih.gov/pubmed/33952518
http://dx.doi.org/10.1126/sciadv.abe7804

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