Cargando…
The SP‐TLR axis, which locally primes the nasal mucosa, is impeded in patients with allergic rhinitis
BACKGROUND: Substance P (SP) and toll‐like receptors (TLRs) contribute to airway disease, particularly during viral infection. We recently demonstrated that SP can act as an initial response to viral stimuli in the upper airway by upregulating TLRs in the nasal epithelia (the SP‐TLR axis). Patients...
Autores principales: | Larsson, Olivia, Sunnergren, Ola, Bachert, Claus, Kumlien Georén, Susanna, Cardell, Lars Olaf |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099340/ https://www.ncbi.nlm.nih.gov/pubmed/33900054 http://dx.doi.org/10.1002/clt2.12009 |
Ejemplares similares
-
Deprived TLR9 Expression in Apparently Healthy Nasal Mucosa Might Trigger Polyp-Growth in Chronic Rhinosinusitis Patients
por: Tengroth, Lotta, et al.
Publicado: (2014) -
Upregulated expression of Notch1/4 - JAG-1/DLL-1 detected in allergic rhinitis
por: Hjalmarsson, Eric, et al.
Publicado: (2023) -
A possible role for neutrophils in allergic rhinitis revealed after cellular subclassification
por: Arebro, Julia, et al.
Publicado: (2017) -
Inverse Immunological Responses Induced by Allergic Rhinitis and Head and Neck Squamous Cell Carcinoma
por: Millrud, Camilla Rydberg, et al.
Publicado: (2014) -
Activation of Activin receptor-like kinases curbs mucosal inflammation and proliferation in chronic rhinosinusitis with nasal polyps
por: Tengroth, Lotta, et al.
Publicado: (2018)