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Impact of study design and statistical model in pharmacogenetic studies with gene‐treatment interaction
Gene‐treatment interactions, just like drug‐drug interactions, can have dramatic effects on a patient response and therefore influence the clinician decision at the patient’s bedside. Crossover designs, although they are known to decrease the number of subjects in drug‐interaction studies, are seldo...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099447/ https://www.ncbi.nlm.nih.gov/pubmed/33951752 http://dx.doi.org/10.1002/psp4.12624 |