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HFD-induced TRAF6 upregulation promotes liver cholesterol accumulation and fatty liver development via EZH2-mediated miR-429/PPARα axis

Despite the increasing prevalence of fatty liver diseases worldwide, the molecular mechanism underlying their pathogenesis remains poorly defined. This study examines the expression and significance of tumor necrosis factor (TNF) receptor-associated factor 6 (TRAF6) in the high-fat diet (HFD)-induce...

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Detalles Bibliográficos
Autores principales:	Zhang, Zhi, Wen, Huiqing, Peng, Bangjian, Weng, Jun, Zeng, Fanhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099485/ https://www.ncbi.nlm.nih.gov/pubmed/33996254 http://dx.doi.org/10.1016/j.omtn.2021.01.026

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