Targeting Cholesterol Metabolism as Efficient Antiviral Strategy Against the Hepatitis E Virus

BACKGROUND AND AIMS: The Hepatitis E virus hijacks the endosomal system for its release. These structures are highly dependent on cholesterol. Hence, this study investigates the impact of HEV on cholesterol-metabolism, the effect of intracellular cholesterol content on HEV-release and the potential...

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Detalles Bibliográficos
Autores principales: Glitscher, Mirco, Martín, David Heiler, Woytinek, Kathrin, Schmidt, Benjamin, Tabari, Denna, Scholl, Catharina, Stingl, Julia C., Seelow, Evelyn, Choi, Mira, Hildt, Eberhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099564/
https://www.ncbi.nlm.nih.gov/pubmed/33601063
http://dx.doi.org/10.1016/j.jcmgh.2021.02.002

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