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Crohn's disease-associated ATG16L1 T300A genotype is associated with improved survival in gastric cancer

BACKGROUND: A non-synonymous single nucleotide polymorphism of the ATG16L1 gene, T300A, is a major Crohn's disease (CD) susceptibility allele, and is known to be associated with increased apoptosis induction in the small intestinal crypt base in CD subjects and mouse models. We hypothesized tha...

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Detalles Bibliográficos
Autores principales: Ma, Changqing, Storer, Chad E., Chandran, Uma, LaFramboise, William A., Petrosko, Patricia, Frank, Madison, Hartman, Douglas J., Pantanowitz, Liron, Haritunians, Talin, Head, Richard D., Liu, Ta-Chiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099593/
https://www.ncbi.nlm.nih.gov/pubmed/33906066
http://dx.doi.org/10.1016/j.ebiom.2021.103347