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Crohn's disease-associated ATG16L1 T300A genotype is associated with improved survival in gastric cancer
BACKGROUND: A non-synonymous single nucleotide polymorphism of the ATG16L1 gene, T300A, is a major Crohn's disease (CD) susceptibility allele, and is known to be associated with increased apoptosis induction in the small intestinal crypt base in CD subjects and mouse models. We hypothesized tha...
Autores principales: | Ma, Changqing, Storer, Chad E., Chandran, Uma, LaFramboise, William A., Petrosko, Patricia, Frank, Madison, Hartman, Douglas J., Pantanowitz, Liron, Haritunians, Talin, Head, Richard D., Liu, Ta-Chiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099593/ https://www.ncbi.nlm.nih.gov/pubmed/33906066 http://dx.doi.org/10.1016/j.ebiom.2021.103347 |
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