Alternative splicing perturbation landscape identifies RNA binding proteins as potential therapeutic targets in cancer

Alternative splicing (AS) plays an important role in gene regulation, and AS perturbations are frequently observed in cancer. RNA binding protein (RBP) is one of the molecular determinants of AS, and perturbations in RBP-gene network activity are causally associated with cancer development. Here, we...

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Detalles Bibliográficos
Autores principales: Li, Junyi, Pan, Tao, Chen, Liuxin, Wang, Qi, Chang, Zhenghong, Zhou, Weiwei, Li, Xinhui, Xu, Gang, Li, Xia, Li, Yongsheng, Zhang, Yunpeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099609/
https://www.ncbi.nlm.nih.gov/pubmed/33996260
http://dx.doi.org/10.1016/j.omtn.2021.04.005

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