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Surgical treatment of metastatic germ cell cancer

Among young men between the ages of 15 and 40 years, germ cell cancer is the most common solid tumor [1]. The worldwide incidence of germ cell cancer is 70 000 cases. Compared to all solid tumors of men, germ cell cancer accounts for 1% of all male tumors. Nevertheless, the mortality of this rare tu...

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Detalles Bibliográficos
Autores principales: Hiester, Andreas, Albers, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Second Military Medical University 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099653/
https://www.ncbi.nlm.nih.gov/pubmed/33996470
http://dx.doi.org/10.1016/j.ajur.2020.05.007
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author Hiester, Andreas
Albers, Peter
author_facet Hiester, Andreas
Albers, Peter
author_sort Hiester, Andreas
collection PubMed
description Among young men between the ages of 15 and 40 years, germ cell cancer is the most common solid tumor [1]. The worldwide incidence of germ cell cancer is 70 000 cases. Compared to all solid tumors of men, germ cell cancer accounts for 1% of all male tumors. Nevertheless, the mortality of this rare tumor entity is about 13% since 9507 patients died worldwide of germ cell cancer. The improvement in survival of germ cell cancer patients is due to a multimodal treatment of germ cell cancer including cisplatin-based chemotherapy and surgery leading to higher cure-rates even in advanced stages [1], whereas the increasing incidence of germ cell cancers cannot be thoroughly explained. In this article we review the current indications for surgery in metastatic germ cell cancers, highlight the strength and weaknesses of techniques and indications and raise the question how to improve surgical treatment in metastatic germ cell cancer.
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spelling pubmed-80996532021-05-13 Surgical treatment of metastatic germ cell cancer Hiester, Andreas Albers, Peter Asian J Urol Review Among young men between the ages of 15 and 40 years, germ cell cancer is the most common solid tumor [1]. The worldwide incidence of germ cell cancer is 70 000 cases. Compared to all solid tumors of men, germ cell cancer accounts for 1% of all male tumors. Nevertheless, the mortality of this rare tumor entity is about 13% since 9507 patients died worldwide of germ cell cancer. The improvement in survival of germ cell cancer patients is due to a multimodal treatment of germ cell cancer including cisplatin-based chemotherapy and surgery leading to higher cure-rates even in advanced stages [1], whereas the increasing incidence of germ cell cancers cannot be thoroughly explained. In this article we review the current indications for surgery in metastatic germ cell cancers, highlight the strength and weaknesses of techniques and indications and raise the question how to improve surgical treatment in metastatic germ cell cancer. Second Military Medical University 2021-04 2020-06-01 /pmc/articles/PMC8099653/ /pubmed/33996470 http://dx.doi.org/10.1016/j.ajur.2020.05.007 Text en © 2021 Editorial Office of Asian Journal of Urology. Production and hosting by Elsevier B.V. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review
Hiester, Andreas
Albers, Peter
Surgical treatment of metastatic germ cell cancer
title Surgical treatment of metastatic germ cell cancer
title_full Surgical treatment of metastatic germ cell cancer
title_fullStr Surgical treatment of metastatic germ cell cancer
title_full_unstemmed Surgical treatment of metastatic germ cell cancer
title_short Surgical treatment of metastatic germ cell cancer
title_sort surgical treatment of metastatic germ cell cancer
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099653/
https://www.ncbi.nlm.nih.gov/pubmed/33996470
http://dx.doi.org/10.1016/j.ajur.2020.05.007
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