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Surgical treatment of metastatic germ cell cancer
Among young men between the ages of 15 and 40 years, germ cell cancer is the most common solid tumor [1]. The worldwide incidence of germ cell cancer is 70 000 cases. Compared to all solid tumors of men, germ cell cancer accounts for 1% of all male tumors. Nevertheless, the mortality of this rare tu...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Second Military Medical University
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099653/ https://www.ncbi.nlm.nih.gov/pubmed/33996470 http://dx.doi.org/10.1016/j.ajur.2020.05.007 |
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author | Hiester, Andreas Albers, Peter |
author_facet | Hiester, Andreas Albers, Peter |
author_sort | Hiester, Andreas |
collection | PubMed |
description | Among young men between the ages of 15 and 40 years, germ cell cancer is the most common solid tumor [1]. The worldwide incidence of germ cell cancer is 70 000 cases. Compared to all solid tumors of men, germ cell cancer accounts for 1% of all male tumors. Nevertheless, the mortality of this rare tumor entity is about 13% since 9507 patients died worldwide of germ cell cancer. The improvement in survival of germ cell cancer patients is due to a multimodal treatment of germ cell cancer including cisplatin-based chemotherapy and surgery leading to higher cure-rates even in advanced stages [1], whereas the increasing incidence of germ cell cancers cannot be thoroughly explained. In this article we review the current indications for surgery in metastatic germ cell cancers, highlight the strength and weaknesses of techniques and indications and raise the question how to improve surgical treatment in metastatic germ cell cancer. |
format | Online Article Text |
id | pubmed-8099653 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Second Military Medical University |
record_format | MEDLINE/PubMed |
spelling | pubmed-80996532021-05-13 Surgical treatment of metastatic germ cell cancer Hiester, Andreas Albers, Peter Asian J Urol Review Among young men between the ages of 15 and 40 years, germ cell cancer is the most common solid tumor [1]. The worldwide incidence of germ cell cancer is 70 000 cases. Compared to all solid tumors of men, germ cell cancer accounts for 1% of all male tumors. Nevertheless, the mortality of this rare tumor entity is about 13% since 9507 patients died worldwide of germ cell cancer. The improvement in survival of germ cell cancer patients is due to a multimodal treatment of germ cell cancer including cisplatin-based chemotherapy and surgery leading to higher cure-rates even in advanced stages [1], whereas the increasing incidence of germ cell cancers cannot be thoroughly explained. In this article we review the current indications for surgery in metastatic germ cell cancers, highlight the strength and weaknesses of techniques and indications and raise the question how to improve surgical treatment in metastatic germ cell cancer. Second Military Medical University 2021-04 2020-06-01 /pmc/articles/PMC8099653/ /pubmed/33996470 http://dx.doi.org/10.1016/j.ajur.2020.05.007 Text en © 2021 Editorial Office of Asian Journal of Urology. Production and hosting by Elsevier B.V. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Review Hiester, Andreas Albers, Peter Surgical treatment of metastatic germ cell cancer |
title | Surgical treatment of metastatic germ cell cancer |
title_full | Surgical treatment of metastatic germ cell cancer |
title_fullStr | Surgical treatment of metastatic germ cell cancer |
title_full_unstemmed | Surgical treatment of metastatic germ cell cancer |
title_short | Surgical treatment of metastatic germ cell cancer |
title_sort | surgical treatment of metastatic germ cell cancer |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099653/ https://www.ncbi.nlm.nih.gov/pubmed/33996470 http://dx.doi.org/10.1016/j.ajur.2020.05.007 |
work_keys_str_mv | AT hiesterandreas surgicaltreatmentofmetastaticgermcellcancer AT alberspeter surgicaltreatmentofmetastaticgermcellcancer |