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Mst1/2 Kinases Inhibitor, XMU-MP-1, Attenuates Angiotensin II-Induced Ascending Aortic Expansion in Hypercholesterolemic Mice
Background: Ascending and abdominal aortic aneurysms (AAs) are asymptomatic, permanent dilations of the aorta with surgical intervention as the currently available therapy. Hippo-Yap signaling cascade plays a critical role in stem cell self-renewal, tissue regeneration and organ size control. By usi...
Autores principales: | Okuyama, Michihiro, Jiang, Weihua, Yang, Lihua, Subramanian, Venkateswaran |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japanese Circulation Society
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099673/ https://www.ncbi.nlm.nih.gov/pubmed/34007939 http://dx.doi.org/10.1253/circrep.CR-20-0104 |
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