Promising therapeutic approaches using CRISPR/Cas9 genome editing technology in the treatment of Duchenne muscular dystrophy

Duchenne muscular dystrophy is an X-linked recessive hereditary monogenic disorder caused by inability to produce dystrophin protein. In most patients, the expression of dystrophin lost due to disrupting mutations in open reading frame. Despite the efforts in a large number of different therapeutic...

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Detalles Bibliográficos
Autores principales: Mollanoori, Hasan, Rahmati, Yazdan, Hassani, Bita, Havasi Mehr, Meysam, Teimourian, Shahram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2020
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099695/
https://www.ncbi.nlm.nih.gov/pubmed/33997161
http://dx.doi.org/10.1016/j.gendis.2019.12.007

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