Multi-center real-world comparison of the fully automated Idylla™ microsatellite instability assay with routine molecular methods and immunohistochemistry on formalin-fixed paraffin-embedded tissue of colorectal cancer

Microsatellite instability (MSI) is present in 15–20% of primary colorectal cancers. MSI status is assessed to detect Lynch syndrome, guide adjuvant chemotherapy, determine prognosis, and use as a companion test for checkpoint blockade inhibitors. Traditionally, MSI status is determined by immunohis...

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Detalles Bibliográficos
Autores principales: Velasco, Ana, Tokat, Fatma, Bonde, Jesper, Trim, Nicola, Bauer, Elisabeth, Meeney, Adam, de Leng, Wendy, Chong, George, Dalstein, Véronique, Kis, Lorand L., Lorentzen, Jon A., Tomić, Snjezana, Thwaites, Keeley, Putzová, Martina, Birnbaum, Astrid, Qazi, Romena, Primmer, Vanessa, Dockhorn-Dworniczak, Barbara, Hernández-Losa, Javier, Soares, Fernando A., Gertler, Asaf A., Kalman, Michal, Wong, Chris, Carraro, Dirce M., Sousa, Ana C., Reis, Rui M., Fox, Stephen B., Fassan, Matteo, Brevet, Marie, Merkelbach-Bruse, Sabine, Colling, Richard, Soilleux, Elizabeth, Teo, Ryan Yee Wei, D’Haene, Nicky, Nolet, Serge, Ristimäki, Ari, Väisänen, Timo, Chapusot, Caroline, Soruri, Afsaneh, Unger, Tina, Wecgowiec, Johanna, Biscuola, Michele, Frattini, Milo, Long, Anna, Campregher, Paulo V, Matias-Guiu, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099763/
https://www.ncbi.nlm.nih.gov/pubmed/33170334
http://dx.doi.org/10.1007/s00428-020-02962-x

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