ent-Kaurane diterpenoids induce apoptosis and ferroptosis through targeting redox resetting to overcome cisplatin resistance

Reactive oxygen species (ROS) induction is an effective mechanism to kill cancer cells for many chemotherapeutics, while resettled redox homeostasis induced by the anticancer drugs will promote cancer chemoresistance. Natural ent-kaurane diterpenoids have been found to bind glutathione (GSH) and sul...

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Detalles Bibliográficos
Autores principales: Sun, Yong, Qiao, Yanan, Liu, Yue, Zhou, Jinchuan, Wang, Xue, Zheng, Hongbo, Xu, Zejun, Zhang, Jiaozhen, Zhou, Yi, Qian, Lilin, Zhang, Chunyang, Lou, Hongxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099784/
https://www.ncbi.nlm.nih.gov/pubmed/33905957
http://dx.doi.org/10.1016/j.redox.2021.101977

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