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The hepatokine fetuin-A disrupts functional maturation of pancreatic beta cells

AIMS/HYPOTHESIS: Neonatal beta cells carry out a programme of postnatal functional maturation to achieve full glucose responsiveness. A partial loss of the mature phenotype of adult beta cells may contribute to a reduction of functional beta cell mass and accelerate the onset of type 2 diabetes. We...

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Detalles Bibliográficos
Autores principales: Gerst, Felicia, Kemter, Elisabeth, Lorza-Gil, Estela, Kaiser, Gabriele, Fritz, Ann-Kathrin, Nano, Rita, Piemonti, Lorenzo, Gauder, Marie, Dahl, Andreas, Nadalin, Silvio, Königsrainer, Alfred, Fend, Falko, Birkenfeld, Andreas L., Wagner, Robert, Heni, Martin, Stefan, Norbert, Wolf, Eckhard, Häring, Hans-Ulrich, Ullrich, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099843/
https://www.ncbi.nlm.nih.gov/pubmed/33765181
http://dx.doi.org/10.1007/s00125-021-05435-1