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KCNQ Channels in the Mesolimbic Reward Circuit Regulate Nociception in Chronic Pain in Mice

Mesocorticolimbic dopaminergic (DA) neurons have been implicated in regulating nociception in chronic pain, yet the mechanisms are barely understood. Here, we found that chronic constructive injury (CCI) in mice increased the firing activity and decreased the KCNQ channel-mediated M-currents in vent...

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Detalles Bibliográficos
Autores principales: Wang, Hao-Ran, Hu, Su-Wan, Zhang, Song, Song, Yu, Wang, Xiao-Yi, Wang, Lei, Li, Yang-Yang, Yu, Yu-Mei, Liu, He, Liu, Di, Ding, Hai-Lei, Cao, Jun-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099961/
https://www.ncbi.nlm.nih.gov/pubmed/33900570
http://dx.doi.org/10.1007/s12264-021-00668-x