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Neutrophil Elastase Defects in Congenital Neutropenia

Severe congenital neutropenia (SCN) is a rare hematological condition with heterogenous genetic background. Neutrophil elastase (NE) encoded by ELANE gene is mutated in over half of the SCN cases. The role of NE defects in myelocytes maturation arrest in bone marrow is widely investigated; however,...

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Detalles Bibliográficos
Autores principales:	Rydzynska, Zuzanna, Pawlik, Bartlomiej, Krzyzanowski, Damian, Mlynarski, Wojciech, Madzio, Joanna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100030/ https://www.ncbi.nlm.nih.gov/pubmed/33968054 http://dx.doi.org/10.3389/fimmu.2021.653932

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