Cargando…

The mouse alpha-globin cluster: a paradigm for studying genome regulation and organization

The mammalian globin gene clusters provide a paradigm for studying the relationship between genome structure and function. As blood stem cells undergo lineage specification and differentiation to form red blood cells, the chromatin structure and expression of the α-globin cluster change. The gradual...

Descripción completa

Detalles Bibliográficos
Autores principales: Oudelaar, A Marieke, Beagrie, Robert A, Kassouf, Mira T, Higgs, Douglas R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100094/
https://www.ncbi.nlm.nih.gov/pubmed/33221670
http://dx.doi.org/10.1016/j.gde.2020.10.003