Acute cigarette smoke or extract exposure rapidly activates TRPA1-mediated calcium influx in primary human airway smooth muscle cells

Tobacco smoking is the largest risk factor for developing chronic obstructive pulmonary disease (COPD), and is associated with hyperresponsiveness of airway smooth muscle (ASM). Chronic exposure to cigarette smoke (CS) leads to airway inflammation and remodelling. However, the direct effect of gaseo...

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Detalles Bibliográficos
Autores principales: Lin, JinHeng, Taggart, Michael, Borthwick, Lee, Fisher, Andrew, Brodlie, Malcolm, Sassano, M. Flori, Tarran, Robert, Gray, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100124/
https://www.ncbi.nlm.nih.gov/pubmed/33953304
http://dx.doi.org/10.1038/s41598-021-89051-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100124/
https://www.ncbi.nlm.nih.gov/pubmed/33953304
http://dx.doi.org/10.1038/s41598-021-89051-4

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