Novel Insights Into Rheumatoid Arthritis Through Characterization of Concordant Changes in DNA Methylation and Gene Expression in Synovial Biopsies of Patients With Differing Numbers of Swollen Joints

In this study, we sought to characterize synovial tissue obtained from individuals with arthralgia and disease-specific auto-antibodies and patients with established rheumatoid arthritis (RA), by applying an integrative multi-omics approach where we investigated differences at the level of DNA methy...

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Detalles Bibliográficos
Autores principales: Li Yim, Andrew Y. F., Ferrero, Enrico, Maratou, Klio, Lewis, Huw D., Royal, George, Tough, David F., Larminie, Chris, Mannens, Marcel M. A. M., Henneman, Peter, de Jonge, Wouter J., van de Sande, Marleen G. H., Gerlag, Danielle M., Prinjha, Rab K., Tak, Paul P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100206/
https://www.ncbi.nlm.nih.gov/pubmed/33968050
http://dx.doi.org/10.3389/fimmu.2021.651475

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