Cargando…
Stimulation of α7-nAChRs coordinates autophagy and apoptosis signaling in experimental knee osteoarthritis
Osteoarthritis (OA) is the most common chronic joint disease in the elderly population. Growing evidence indicates that a balance between autophagy and apoptosis in chondrocytes plays a key role in OA’s cartilage degradation. Thus, drugs targeting the balance between apoptosis and autophagy are pote...
Autores principales: | Liu, Yuan, Xu, Shi, Zhang, Haijun, Qian, Kaoliang, Huang, Jiachen, Gu, Xianger, Li, Yan, Fan, Yi, Hu, Jun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100296/ https://www.ncbi.nlm.nih.gov/pubmed/33953172 http://dx.doi.org/10.1038/s41419-021-03726-4 |
Ejemplares similares
-
Residues Responsible for the Selectivity of α-Conotoxins for Ac-AChBP or nAChRs
por: Lin, Bo, et al.
Publicado: (2016) -
The Regulation Effect of α7nAChRs and M1AChRs on Inflammation and Immunity in Sepsis
por: Hu, Song, et al.
Publicado: (2021) -
Semisynthetic
Analogues of Toxiferine I and Their
Pharmacological Properties at α7 nAChRs, Muscle-Type nAChRs,
and the Allosteric Binding Site of Muscarinic M(2) Receptors
por: Zlotos, Darius P., et al.
Publicado: (2014) -
Characterization of HA-tagged α9 and α10 nAChRs in the mouse cochlea
por: Vyas, Pankhuri, et al.
Publicado: (2020) -
Unique Pharmacological Properties of α-Conotoxin OmIA at α7 nAChRs
por: Ho, Thao N.T., et al.
Publicado: (2021)