Cargando…

Downregulation of GLYAT Facilitates Tumor Growth and Metastasis and Poor Clinical Outcomes Through the PI3K/AKT/Snail Pathway in Human Breast Cancer

BACKGROUND: The Glycine N-acyltransferase (GLYAT) gene encodes a protein that catalyzes the transfer of acyl groups from acyl CoA to glycine, resulting in acyl glycine and coenzyme A. Aberrant GLYAT expression is associated with several malignant tumors, but its clinical importance in human breast c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tian, Xin, Wu, Lina, Jiang, Min, Zhang, Zhenyong, Wu, Rong, Miao, Jianing, Liu, Caigang, Gao, Song
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100313/ https://www.ncbi.nlm.nih.gov/pubmed/33968740 http://dx.doi.org/10.3389/fonc.2021.641399

Ejemplares similares

Corrigendum: Downregulation of GLYAT Facilitates Tumor Growth and Metastasis and Poor Clinical Outcomes Through the PI3K/AKT/Snail Pathway in Human Breast Cancer
por: Tian, Xin, et al.
Publicado: (2022)

GLYAT regulates JNK-mediated cell death in Drosophila
por: Ren, Pu, et al.
Publicado: (2017)

MRPS16 facilitates tumor progression via the PI3K/AKT/Snail signaling axis
por: Wang, Zhen, et al.
Publicado: (2020)

THBS1-Mediated Degradation of Collagen via the PI3K/AKT Pathway Facilitates the Metastasis and Poor Prognosis of OSCC
por: Wen, Zhihao, et al.
Publicado: (2023)

dGLYAT modulates Gadd45-mediated JNK activation and cell invasion
por: Xu, Meng, et al.
Publicado: (2022)

STC2 promotes head and neck squamous cell carcinoma metastasis through modulating the PI3K/AKT/Snail signaling
por: Yang, Shuwen, et al.
Publicado: (2016)

MST4 negatively regulates the EMT, invasion and metastasis of HCC cells by inactivating PI3K/AKT/Snail1 axis
por: Dian, Mei-Juan, et al.
Publicado: (2021)

microRNA-582 Potentiates Liver and Lung Metastasis of Gastric Carcinoma Cells Through the FOXO3-Mediated PI3K/Akt/Snail Pathway
por: Xie, Tianyu, et al.
Publicado: (2020)

miR-126 suppresses epithelial-to-mesenchymal transition and metastasis by targeting PI3K/AKT/Snail signaling of lung cancer cells
por: Jia, Zhijun, et al.
Publicado: (2018)

PRMT9 promotes hepatocellular carcinoma invasion and metastasis via activating PI3K/Akt/GSK‐3β/Snail signaling
por: Jiang, Hai, et al.
Publicado: (2018)

The glycine N-acyltransferases, GLYAT and GLYATL1, contribute to the detoxification of isovaleryl-CoA - an in-silico and in vitro validation
por: Kühn, Stefan, et al.
Publicado: (2023)

TRIM59 facilitates the proliferation of colorectal cancer and promotes metastasis via the PI3K/AKT pathway
por: Sun, Ye, et al.
Publicado: (2017)

Downregulation of BRD4 inhibits gallbladder cancer proliferation and metastasis and induces apoptosis via PI3K/AKT pathway
por: Hao, Jiaqi, et al.
Publicado: (2017)

8-Hydroxydaidzein Downregulates JAK/STAT, MMP, Oxidative Phosphorylation, and PI3K/AKT Pathways in K562 Cells
por: Wu, Pei-Shan, et al.
Publicado: (2021)

LncRNA LINC00460 facilitates the proliferation and metastasis of renal cell carcinoma via PI3K/AKT signaling pathway
por: Zhou, Feng-Juan, et al.
Publicado: (2022)

NETO2 promotes invasion and metastasis of gastric cancer cells via activation of PI3K/Akt/NF-κB/Snail axis and predicts outcome of the patients
por: Liu, Jun-yan, et al.
Publicado: (2019)

GPX2 promotes EMT and metastasis in non‐small cell lung cancer by activating PI3K/AKT/mTOR/Snail signaling axis
por: Peng, Fang, et al.
Publicado: (2023)

Downregulation of FAP suppresses cell proliferation and metastasis through PTEN/PI3K/AKT and Ras-ERK signaling in oral squamous cell carcinoma
por: Wang, H, et al.
Publicado: (2014)

Psoralidin inhibits osteosarcoma growth and metastasis by downregulating ITGB1 expression via the FAK and PI3K/Akt signaling pathways
por: Cheng, Shengwen, et al.
Publicado: (2023)

Downregulated F-Box/LRR-Repeat Protein 7 Facilitates Pancreatic Cancer Metastasis by Regulating Snail1 for Proteasomal Degradation
por: Tang, Liang, et al.
Publicado: (2021)

FAM83A signaling induces epithelial-mesenchymal transition by the PI3K/AKT/Snail pathway in NSCLC
por: Zhou, Fengrui, et al.
Publicado: (2019)

RPN2 Predicts Poor Prognosis and Promotes Bladder Cancer Growth and Metastasis via the PI3K-Akt Pathway
por: Han, Chenglin, et al.
Publicado: (2021)

CORO1C is Associated With Poor Prognosis and Promotes Metastasis Through PI3K/AKT Pathway in Colorectal Cancer
por: Wang, Zongxia, et al.
Publicado: (2021)

BCL11A Facilitates Cell Proliferation and Metastasis in Neuroblastoma via Regulating the PI3K/Akt Signaling Pathway
por: Jin, Qianya, et al.
Publicado: (2022)

Periostin promotes the proliferation and metastasis of osteosarcoma by increasing cell survival and activates the PI3K/Akt pathway
por: Xu, Chaojian, et al.
Publicado: (2022)

Beauvericin Ameliorates Experimental Colitis by Inhibiting Activated T Cells via Downregulation of the PI3K/Akt Signaling Pathway
por: Wu, Xue-Feng, et al.
Publicado: (2013)

CTGF facilitates cell‐cell communication in chondrocytes via PI3K/Akt signalling pathway
por: Wu, Zuping, et al.
Publicado: (2021)

Downregulation of PI3K/AKT/mTOR Pathway in Juglone-Treated Bovine Oocytes
por: El-Sheikh, Marwa, et al.
Publicado: (2023)

Wip1 suppresses ovarian cancer metastasis through the ATM/AKT/Snail mediated signaling
por: Yin, Sheng, et al.
Publicado: (2016)

YBX3 Mediates the Metastasis of Nasopharyngeal Carcinoma via PI3K/AKT Signaling
por: Fan, Xiaoqin, et al.
Publicado: (2021)

Clinical implications of Girdin and PI3K protein expression in breast cancer
por: JIN, FENG, et al.
Publicado: (2013)

14‐3‐3ζ promotes gliomas cells invasion by regulating Snail through the PI3K/AKT signaling
por: Li, Junjun, et al.
Publicado: (2019)

Telocinobufagin inhibits the epithelial-to-mesenchymal transition of breast cancer cells through the PI3K/Akt/Snail signaling pathway
por: Gao, Yuxue, et al.
Publicado: (2021)

Corrigendum: CORO1C is Associated with Poor Prognosis and Promotes Metastasis Through PI3K/AKT Pathway in Colorectal Cancer
por: Wang, Zongxia, et al.
Publicado: (2021)

α-Mangostin Suppresses the Viability and Epithelial-Mesenchymal Transition of Pancreatic Cancer Cells by Downregulating the PI3K/Akt Pathway
por: Xu, Qinhong, et al.
Publicado: (2014)

Downregulation of miR-133a-3p promotes prostate cancer bone metastasis via activating PI3K/AKT signaling
por: Tang, Yubo, et al.
Publicado: (2018)

Aclidinium inhibits proliferation and metastasis of ovarian cancer SKOV3 cells via downregulating PI3K/AKT/mTOR signaling pathway
por: Qiao, Juan, et al.
Publicado: (2018)

PI3K/AKT/mTOR Signaling Pathway Is Downregulated by Runzaoling (RZL) in Sjögren's Syndrome
por: Zeng, Ping, et al.
Publicado: (2022)

MUC15 inhibits cancer metastasis via PI3K/AKT signaling in renal cell carcinoma
por: Yue, Yangyang, et al.
Publicado: (2020)

Ceramide Synthase 1 Inhibits Brain Metastasis of Non-Small Cell Lung Cancer by Interacting with USP14 and Downregulating the PI3K/AKT/mTOR Signaling Pathway
por: Xu, Yiquan, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_3bkqoftvrjfan3pi6goep908q5