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SphK2/S1P Promotes Metastasis of Triple-Negative Breast Cancer Through the PAK1/LIMK1/Cofilin1 Signaling Pathway

BACKGROUND: Triple-negative breast cancer (TNBC) features a poor prognosis, which is partially attributed to its high metastatic rate. However, there is no effective target for systemic TNBC therapy due to the absence of estrogen, progesterone, and human epidermal growth factor 2 receptors (ER, PR,...

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Detalles Bibliográficos
Autores principales:	Shi, Weiwei, Ma, Ding, Cao, Yin, Hu, Lili, Liu, Shuwen, Yan, Dongliang, Zhang, Shan, Zhang, Guang, Wang, Zhongxia, Wu, Junhua, Jiang, Chunping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100449/ https://www.ncbi.nlm.nih.gov/pubmed/33968977 http://dx.doi.org/10.3389/fmolb.2021.598218

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