Detection of Imatinib Based on Electrochemical Sensor Constructed Using Biosynthesized Graphene-Silver Nanocomposite

The establishment of a monitoring technique for imatinib is necessary in clinical and environmental toxicology. Leaf extracts of Lycoris longituba were used as reducing agent for the one-step synthesis of reduced graphene oxide-Ag nanocomposites. This nanocomposite was characterized by TEM, FTIR, XR...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Zhen, Liu, Jingjing, Liang, Minmin, Zheng, Haoyue, Zhu, Chuansheng, Wang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100453/
https://www.ncbi.nlm.nih.gov/pubmed/33968906
http://dx.doi.org/10.3389/fchem.2021.670074
_version_ 1783688792709791744
author Wu, Zhen
Liu, Jingjing
Liang, Minmin
Zheng, Haoyue
Zhu, Chuansheng
Wang, Yan
author_facet Wu, Zhen
Liu, Jingjing
Liang, Minmin
Zheng, Haoyue
Zhu, Chuansheng
Wang, Yan
author_sort Wu, Zhen
collection PubMed
description The establishment of a monitoring technique for imatinib is necessary in clinical and environmental toxicology. Leaf extracts of Lycoris longituba were used as reducing agent for the one-step synthesis of reduced graphene oxide-Ag nanocomposites. This nanocomposite was characterized by TEM, FTIR, XRD, and other instruments. Then, the graphene/Ag nanocomposite was used as a modifier to be cemented on the surface of the glassy carbon electrode. This electrode exhibited excellent electrochemical sensing performance. Under the optimal conditions, the proposed electrode could detect imatinib at 10 nM−0.28 mM with a low limit of detection. This electrochemical sensor also has excellent anti-interference performance and reproducibility.
format Online
Article
Text
id pubmed-8100453
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-81004532021-05-07 Detection of Imatinib Based on Electrochemical Sensor Constructed Using Biosynthesized Graphene-Silver Nanocomposite Wu, Zhen Liu, Jingjing Liang, Minmin Zheng, Haoyue Zhu, Chuansheng Wang, Yan Front Chem Chemistry The establishment of a monitoring technique for imatinib is necessary in clinical and environmental toxicology. Leaf extracts of Lycoris longituba were used as reducing agent for the one-step synthesis of reduced graphene oxide-Ag nanocomposites. This nanocomposite was characterized by TEM, FTIR, XRD, and other instruments. Then, the graphene/Ag nanocomposite was used as a modifier to be cemented on the surface of the glassy carbon electrode. This electrode exhibited excellent electrochemical sensing performance. Under the optimal conditions, the proposed electrode could detect imatinib at 10 nM−0.28 mM with a low limit of detection. This electrochemical sensor also has excellent anti-interference performance and reproducibility. Frontiers Media S.A. 2021-04-22 /pmc/articles/PMC8100453/ /pubmed/33968906 http://dx.doi.org/10.3389/fchem.2021.670074 Text en Copyright © 2021 Wu, Liu, Liang, Zheng, Zhu and Wang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Chemistry
Wu, Zhen
Liu, Jingjing
Liang, Minmin
Zheng, Haoyue
Zhu, Chuansheng
Wang, Yan
Detection of Imatinib Based on Electrochemical Sensor Constructed Using Biosynthesized Graphene-Silver Nanocomposite
title Detection of Imatinib Based on Electrochemical Sensor Constructed Using Biosynthesized Graphene-Silver Nanocomposite
title_full Detection of Imatinib Based on Electrochemical Sensor Constructed Using Biosynthesized Graphene-Silver Nanocomposite
title_fullStr Detection of Imatinib Based on Electrochemical Sensor Constructed Using Biosynthesized Graphene-Silver Nanocomposite
title_full_unstemmed Detection of Imatinib Based on Electrochemical Sensor Constructed Using Biosynthesized Graphene-Silver Nanocomposite
title_short Detection of Imatinib Based on Electrochemical Sensor Constructed Using Biosynthesized Graphene-Silver Nanocomposite
title_sort detection of imatinib based on electrochemical sensor constructed using biosynthesized graphene-silver nanocomposite
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100453/
https://www.ncbi.nlm.nih.gov/pubmed/33968906
http://dx.doi.org/10.3389/fchem.2021.670074
work_keys_str_mv AT wuzhen detectionofimatinibbasedonelectrochemicalsensorconstructedusingbiosynthesizedgraphenesilvernanocomposite
AT liujingjing detectionofimatinibbasedonelectrochemicalsensorconstructedusingbiosynthesizedgraphenesilvernanocomposite
AT liangminmin detectionofimatinibbasedonelectrochemicalsensorconstructedusingbiosynthesizedgraphenesilvernanocomposite
AT zhenghaoyue detectionofimatinibbasedonelectrochemicalsensorconstructedusingbiosynthesizedgraphenesilvernanocomposite
AT zhuchuansheng detectionofimatinibbasedonelectrochemicalsensorconstructedusingbiosynthesizedgraphenesilvernanocomposite
AT wangyan detectionofimatinibbasedonelectrochemicalsensorconstructedusingbiosynthesizedgraphenesilvernanocomposite

Ejemplares similares