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CYP3A5 and UGT1A9 Polymorphisms Influence Immunosuppressive Therapy in Pediatric Kidney Transplant Recipients

Background: Tacrolimus (TAC) and mycophenolic acid (MPA) are the main immunosuppressive drugs used in pediatric kidney transplantation. Single nucleotide polymorphisms (SNPs) in metabolizing enzymes and transporters might influence plasma levels of these drugs. Herein, we sought to determine the inf...

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Detalles Bibliográficos
Autores principales:	Krall, Paola, Yañez, Dominique, Rojo, Angélica, Delucchi, Ángela, Córdova, Miguel, Morales, Jorge, Boza, Pía, de la Rivera, Alonso, Espinoza, Natalie, Armijo, Natalia, Castañeda, Luis E., Farfán, Mauricio J., Salas, Carolina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100460/ https://www.ncbi.nlm.nih.gov/pubmed/33967795 http://dx.doi.org/10.3389/fphar.2021.653525

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