Colchicine Blocks Tubulin Heterodimer Recycling by Tubulin Cofactors TBCA, TBCB, and TBCE

Colchicine has been used to treat gout and, more recently, to effectively prevent autoinflammatory diseases and both primary and recurrent episodes of pericarditis. The anti-inflammatory action of colchicine seems to result from irreversible inhibition of tubulin polymerization and microtubule (MT)...

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Detalles Bibliográficos
Autores principales: Nolasco, Sofia, Bellido, Javier, Serna, Marina, Carmona, Bruno, Soares, Helena, Zabala, Juan Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100514/
https://www.ncbi.nlm.nih.gov/pubmed/33968934
http://dx.doi.org/10.3389/fcell.2021.656273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100514/
https://www.ncbi.nlm.nih.gov/pubmed/33968934
http://dx.doi.org/10.3389/fcell.2021.656273

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