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Coiled-Coil Domain-Containing 68 Downregulation Promotes Colorectal Cancer Cell Growth by Inhibiting ITCH-Mediated CDK4 Degradation

Coiled-coil domain-containing 68 (CCDC68) plays different roles in cancer and is predicted as a tumor suppressor in human colorectal cancer (CRC). However, the specific role of CCDC68 in CRC and the underlying mechanisms remain unknown. Here, we showed that CCDC68 expression was lower in CRC than th...

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Detalles Bibliográficos
Autores principales:	Wang, Cong, Li, Hongyan, Wu, Lei, Jiao, Xueli, Jin, Zihui, Zhu, Yujie, Fang, Ziling, Zhang, Xiaodong, Huang, Haishan, Zhao, Lingling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100586/ https://www.ncbi.nlm.nih.gov/pubmed/33968776 http://dx.doi.org/10.3389/fonc.2021.668743

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