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Pro-Resolving Mediator Annexin A1 Regulates Intracellular Ca(2+) and Mucin Secretion in Cultured Goblet Cells Suggesting a New Use in Inflammatory Conjunctival Diseases
The amount of mucin secreted by conjunctival goblet cells is regulated to ensure the optimal level for protection of the ocular surface. Under physiological conditions lipid specialized pro-resolving mediators (SPM) are essential for maintaining tissue homeostasis including the conjunctiva. The prot...
Autores principales: | Lyngstadaas, Anne V., Olsen, Markus V., Bair, Jeffrey A., Hodges, Robin R., Utheim, Tor P., Serhan, Charles N., Dartt, Darlene A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100605/ https://www.ncbi.nlm.nih.gov/pubmed/33968020 http://dx.doi.org/10.3389/fimmu.2021.618653 |
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