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Novel bi-allelic mutations in DNAH1 cause multiple morphological abnormalities of the sperm flagella resulting in male infertility

BACKGROUND: Male infertility is a major health concern and approximately 10–15% of cases are caused by genetic abnormalities. Defects in the sperm flagella are closely related to male infertility, since flagellar beating allows sperm to swim. The sperm of males afflicted with multiple morphological...

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Detalles Bibliográficos
Autores principales: Jiang, Chuan, Zhang, Xueguang, Zhang, Heng, Guo, Junliang, Zhang, Chaoliang, Li, Jinhong, Yang, Yihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100829/
https://www.ncbi.nlm.nih.gov/pubmed/33968654
http://dx.doi.org/10.21037/tau-20-1434