The combination of microRNA-371a-3p and 375-5p can distinguish viable germ cell tumor and teratoma from necrosis in postchemotherapy retroperitoneal lymph node dissection specimens

BACKGROUND: To identify a combination of microRNAs (miRNA) to differentiate between viable tumor (V) or teratoma (T) and necrosis/fibrosis (N) in pcRPLND specimens of metastatic germ cell tumor (GCT) patients with residual masses ≥1 cm after chemotherapy. Biomarker guided therapy could reduce overtr...

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Detalles Bibliográficos
Autores principales: Kremer, Lara, von Brandenstein, Melanie, Wittersheim, Maike, Koeditz, Barbara, Paffenholz, Pia, Hellmich, Martin, Pfister, David, Heidenreich, Axel, Nestler, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100847/
https://www.ncbi.nlm.nih.gov/pubmed/33968653
http://dx.doi.org/10.21037/tau-20-1349

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