Cargando…

Detection of retinal and blood Aβ oligomers with nanobodies

INTRODUCTION: Abnormal retinal changes are increasingly recognized as an early pathological change in Alzheimer's disease (AD). Although amyloid beta oligomers (Aβo) have been shown to accumulate in the blood and retina of AD patients and animals, it is not known whether the early Aβo depositio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Habiba, Umma, Descallar, Joseph, Kreilaus, Fabian, Adhikari, Utpal K., Kumar, Sachin, Morley, John W, Bui, Bang V, Koronyo‐Hamaoui, Maya, Tayebi, Mourad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Retinal Imaging
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8101010/ https://www.ncbi.nlm.nih.gov/pubmed/33977118 http://dx.doi.org/10.1002/dad2.12193

Ejemplares similares

Sectoral segmentation of retinal amyloid imaging in subjects with cognitive decline
por: Dumitrascu, Oana M., et al.
Publicado: (2020)

Neuronal Deposition of Amyloid-β Oligomers and Hyperphosphorylated Tau Is Closely Connected with Cognitive Dysfunction in Aged Dogs
por: Habiba, Umma, et al.
Publicado: (2021)

Retinal phenotyping of variants of Alzheimer's disease using ultra‐widefield retinal images
por: Csincsik, Lajos, et al.
Publicado: (2021)

Retinal microvascular network attenuation in Alzheimer's disease
por: Williams, Michael A., et al.
Publicado: (2015)

Nonvascular retinal imaging markers of preclinical Alzheimer's disease
por: Snyder, Peter J., et al.
Publicado: (2016)

Retinal oxygen metabolism in patients with mild cognitive impairment
por: Olafsdottir, Olof Birna, et al.
Publicado: (2018)

A recommended “minimum data set” framework for SD‐OCT retinal image acquisition and analysis from the Atlas of Retinal Imaging in Alzheimer's Study (ARIAS)
por: Alber, Jessica, et al.
Publicado: (2020)

Retinal blood flow in mild cognitive impairment and Alzheimer's disease
por: Feke, Gilbert T., et al.
Publicado: (2015)

Is retinal vasculature a biomarker in amyloid proven Alzheimer's disease?
por: den Haan, Jurre, et al.
Publicado: (2019)

Change in retinal structural anatomy during the preclinical stage of Alzheimer's disease
por: Santos, Cláudia Y., et al.
Publicado: (2018)

Retinal microvascular features and cognitive change in the Lothian-Birth Cohort 1936
por: McGrory, Sarah, et al.
Publicado: (2019)

The application of retinal fundus camera imaging in dementia: A systematic review
por: McGrory, Sarah, et al.
Publicado: (2016)

Retinal thickness in Alzheimer's disease: A systematic review and meta-analysis
por: den Haan, Jurre, et al.
Publicado: (2017)

Abnormal retinal capillary blood flow in autosomal dominant Alzheimer's disease
por: Singer, Maxwell B., et al.
Publicado: (2021)

Retinal arteriolar parameters as a surrogate marker of intracranial vascular pathology
por: Abdelhak, Ahmed, et al.
Publicado: (2022)

Retinal thickness correlates with parietal cortical atrophy in early-onset Alzheimer's disease and controls
por: den Haan, Jurre, et al.
Publicado: (2017)

Perifovea retinal thickness as an ophthalmic biomarker for mild cognitive impairment and early Alzheimer's disease
por: Tao, Rui, et al.
Publicado: (2019)

Lower retinal capillary density in minimal cognitive impairment among older Latinx adults
por: Ashimatey, Bright S., et al.
Publicado: (2020)

Age-related retinal thickness in Down's syndrome: A high-risk population for dementia
por: Walpert, Madeleine J., et al.
Publicado: (2019)

The retinal choroid as an oculovascular biomarker for Alzheimer's dementia: A histopathological study in severe disease
por: Asanad, Samuel, et al.
Publicado: (2019)

Retinal thickness as a potential biomarker in patients with amyloid-proven early- and late-onset Alzheimer's disease
por: den Haan, Jurre, et al.
Publicado: (2019)

Retinal imaging demonstrates reduced capillary density in clinically unimpaired APOE ε4 gene carriers
por: Elahi, Fanny M., et al.
Publicado: (2021)

Retinal nerve fiber layer thickness in amnestic mild cognitive impairment: Case-control study and meta-analysis
por: Knoll, Brianna, et al.
Publicado: (2016)

Retinal ganglion cell–inner plexiform layer thickness is nonlinearly associated with cognitive impairment in the community-dwelling elderly
por: Liu, Yao-Lin, et al.
Publicado: (2018)

A systematic review and meta-analysis of retinal nerve fiber layer change in dementia, using optical coherence tomography
por: Thomson, Kelsey L., et al.
Publicado: (2015)

Feasibility study for detection of retinal amyloid in clinical trials: The Anti‐Amyloid Treatment in Asymptomatic Alzheimer's Disease (A4) trial
por: Ngolab, Jennifer, et al.
Publicado: (2021)

Correlation between cognitive impairment and retinal neural loss assessed by swept-source optical coherence tomography in patients with mild cognitive impairment
por: Almeida, Ana L.M., et al.
Publicado: (2019)

Thicker macula in asymptomatic APOE Ɛ4 middle‐aged adults at high AD risk
por: Rotenstreich, Ygal, et al.
Publicado: (2022)

AAV2-mediated GRP78 Transfer Alleviates Retinal Neuronal Injury by Downregulating ER Stress and Tau Oligomer Formation
por: Ha, Yonju, et al.
Publicado: (2018)

Choroidal thinning: Alzheimer's disease and aging
por: Cunha, João Paulo, et al.
Publicado: (2017)

Increased choroidal thickness in adults with Down syndrome
por: Csincsik, Lajos, et al.
Publicado: (2021)

The application of optical coherence tomography angiography in Alzheimer's disease: A systematic review
por: Rifai, Olivia M., et al.
Publicado: (2021)

Retinal capillary degeneration and blood-retinal barrier disruption in murine models of Alzheimer’s disease
por: Shi, Haoshen, et al.
Publicado: (2020)

Analysis of imaging biomarkers and retinal nerve fiber layer thickness in RPGR-associated retinitis pigmentosa
por: Birtel, Theresa H., et al.
Publicado: (2021)

Retinal Vasculopathy in Alzheimer’s Disease
por: Shi, Haoshen, et al.
Publicado: (2021)

The learning curve of retinal detachment surgery
por: Radeck, Viola, et al.
Publicado: (2021)

The usefulness of the retinal sensitivity measurement with a microperimetry for predicting the visual prognosis of branch retinal vein occlusion with macular edema
por: Fujino, Ryosuke, et al.
Publicado: (2020)

Retinal venous pressure is decreased after anti-VEGF therapy in patients with retinal vein occlusion–related macular edema
por: Kida, Teruyo, et al.
Publicado: (2021)

Blindness and visual impairment due to retinal diseases
por: Shah, Shaheen
Publicado: (2009)

Rhegmatogenous retinal detachment following intravitreal ocriplasmin
por: Madi, Haifa A., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_gat86knchmvddnu0v4a39b9d02