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CircPTK2-miR-181c-5p-HMGB1: a new regulatory pathway for microglia activation and hippocampal neuronal apoptosis induced by sepsis

BACKGROUND: Circular RNA hsa_circ_0008305 (circPTK2), miR-181c-5p and High mobility group box-1 (HMGB1) had a targeted regulatory relationship through bioinformatics analysis. This study explained the effects of these genes in microglia and sepsis mice. METHODS: Lipopolysaccharide (LPS) or Cecal Lig...

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Detalles Bibliográficos
Autores principales:	Li, Min, Hu, Junwen, Peng, Yucong, Li, Jingbo, Ren, Reng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8101146/ https://www.ncbi.nlm.nih.gov/pubmed/33952191 http://dx.doi.org/10.1186/s10020-021-00305-3

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