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Costs associated with depression and obesity among cardiovascular patients: medical expenditure panel survey analysis

BACKGROUND: There is a lack of information on the cost of depression associated with metabolic syndrome and cardiovascular diseases in the literature. METHODS: We evaluated the synergistic effects of depression and obesity on total expenditures for cardiovascular conditions using data from the Medic...

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Autores principales: Tápias, Felipe Saia, Otani, Victor Henrique Oyamada, Vasques, Daniel Augusto Corrêa, Otani, Thais Zelia Santos, Uchida, Ricardo Riyoiti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8101168/
https://www.ncbi.nlm.nih.gov/pubmed/33957919
http://dx.doi.org/10.1186/s12913-021-06428-x
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author Tápias, Felipe Saia
Otani, Victor Henrique Oyamada
Vasques, Daniel Augusto Corrêa
Otani, Thais Zelia Santos
Uchida, Ricardo Riyoiti
author_facet Tápias, Felipe Saia
Otani, Victor Henrique Oyamada
Vasques, Daniel Augusto Corrêa
Otani, Thais Zelia Santos
Uchida, Ricardo Riyoiti
author_sort Tápias, Felipe Saia
collection PubMed
description BACKGROUND: There is a lack of information on the cost of depression associated with metabolic syndrome and cardiovascular diseases in the literature. METHODS: We evaluated the synergistic effects of depression and obesity on total expenditures for cardiovascular conditions using data from the Medical Expenditure Panel Survey (MEPS) database. We analyzed MEPS data from 1996 to 2017 comprising adult cardiovascular subjects. We categorized individuals following a combination of International Classification of Diseases ICD-9-CM and ICD-10 codes, and depression symptoms as evaluated using the Patient Health Questionnaire-2 (PHQ-2) depression screening tool. Our sample comprised cardiovascular patients aged 18 years and older, with a body mass index (BMI) between 18.5 and 60. Our study comprised unweighted sample of 96,697 (weighted sample of 938,835,031) adults, a US-nationwide representative sample of cardiovascular disease patients. The four response categories were: no depression; unrecognized depression; asymptomatic depression; and symptomatic depression. Our evaluated outcomes were total annual healthcare expenditures, including dental, emergency room, hospital outpatient, hospital inpatient, office-based, prescription, and home health care expenses. RESULTS: Asymptomatic and symptomatic depression was more frequent among obese individuals than in individuals with a normal BMI (p <  0.001). Total expenditure was highest among symptomatic depression individuals (17,536) and obese (9871) with cardiovascular disease. All the expenditure outcomes were significantly higher among symptomatic depression individuals than those without depression (p <  0.001), except for dental costs. All healthcare expenditures associated with obesity were higher compared to individuals with normal BMI with p <  0.001, except for emergency and home healthcare costs. Most importantly, among obese individuals, all healthcare expenditures were significantly higher (p <  0.001) in those with symptomatic depression than those without depression, except for dental costs, where the difference was not significant (0.899). Therefore, obesity and depression entail increased expenses in patients with cardiovascular disease. CONCLUSIONS: We found incremental expenditures among unrecognized, asymptomatic, and symptomatic depressed individuals with obesity compared to non-depressed, non-obese subjects. However, these are preliminary results that should be further validated using different methodologies.
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spelling pubmed-81011682021-05-06 Costs associated with depression and obesity among cardiovascular patients: medical expenditure panel survey analysis Tápias, Felipe Saia Otani, Victor Henrique Oyamada Vasques, Daniel Augusto Corrêa Otani, Thais Zelia Santos Uchida, Ricardo Riyoiti BMC Health Serv Res Research Article BACKGROUND: There is a lack of information on the cost of depression associated with metabolic syndrome and cardiovascular diseases in the literature. METHODS: We evaluated the synergistic effects of depression and obesity on total expenditures for cardiovascular conditions using data from the Medical Expenditure Panel Survey (MEPS) database. We analyzed MEPS data from 1996 to 2017 comprising adult cardiovascular subjects. We categorized individuals following a combination of International Classification of Diseases ICD-9-CM and ICD-10 codes, and depression symptoms as evaluated using the Patient Health Questionnaire-2 (PHQ-2) depression screening tool. Our sample comprised cardiovascular patients aged 18 years and older, with a body mass index (BMI) between 18.5 and 60. Our study comprised unweighted sample of 96,697 (weighted sample of 938,835,031) adults, a US-nationwide representative sample of cardiovascular disease patients. The four response categories were: no depression; unrecognized depression; asymptomatic depression; and symptomatic depression. Our evaluated outcomes were total annual healthcare expenditures, including dental, emergency room, hospital outpatient, hospital inpatient, office-based, prescription, and home health care expenses. RESULTS: Asymptomatic and symptomatic depression was more frequent among obese individuals than in individuals with a normal BMI (p <  0.001). Total expenditure was highest among symptomatic depression individuals (17,536) and obese (9871) with cardiovascular disease. All the expenditure outcomes were significantly higher among symptomatic depression individuals than those without depression (p <  0.001), except for dental costs. All healthcare expenditures associated with obesity were higher compared to individuals with normal BMI with p <  0.001, except for emergency and home healthcare costs. Most importantly, among obese individuals, all healthcare expenditures were significantly higher (p <  0.001) in those with symptomatic depression than those without depression, except for dental costs, where the difference was not significant (0.899). Therefore, obesity and depression entail increased expenses in patients with cardiovascular disease. CONCLUSIONS: We found incremental expenditures among unrecognized, asymptomatic, and symptomatic depressed individuals with obesity compared to non-depressed, non-obese subjects. However, these are preliminary results that should be further validated using different methodologies. BioMed Central 2021-05-06 /pmc/articles/PMC8101168/ /pubmed/33957919 http://dx.doi.org/10.1186/s12913-021-06428-x Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Tápias, Felipe Saia
Otani, Victor Henrique Oyamada
Vasques, Daniel Augusto Corrêa
Otani, Thais Zelia Santos
Uchida, Ricardo Riyoiti
Costs associated with depression and obesity among cardiovascular patients: medical expenditure panel survey analysis
title Costs associated with depression and obesity among cardiovascular patients: medical expenditure panel survey analysis
title_full Costs associated with depression and obesity among cardiovascular patients: medical expenditure panel survey analysis
title_fullStr Costs associated with depression and obesity among cardiovascular patients: medical expenditure panel survey analysis
title_full_unstemmed Costs associated with depression and obesity among cardiovascular patients: medical expenditure panel survey analysis
title_short Costs associated with depression and obesity among cardiovascular patients: medical expenditure panel survey analysis
title_sort costs associated with depression and obesity among cardiovascular patients: medical expenditure panel survey analysis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8101168/
https://www.ncbi.nlm.nih.gov/pubmed/33957919
http://dx.doi.org/10.1186/s12913-021-06428-x
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