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Molecular characterization of HLA class II binding to the LAG‐3 T cell co‐inhibitory receptor
Immune checkpoint inhibitors (antibodies that block the T cell co‐inhibitory receptors PD‐1/PD‐L1 or CTLA‐4) have revolutionized the treatment of some forms of cancer. Importantly, combination approaches using drugs that target both pathways have been shown to boost the efficacy of such treatments....
Autores principales: | MacLachlan, Bruce J., Mason, Georgina H., Greenshields‐Watson, Alexander, Triebel, Frederic, Gallimore, Awen, Cole, David K., Godkin, Andrew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8101287/ https://www.ncbi.nlm.nih.gov/pubmed/32920841 http://dx.doi.org/10.1002/eji.202048753 |
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