Docosahexanoic acid signals through the Nrf2–Nqo1 pathway to maintain redox balance and promote neurite outgrowth

Evidence suggests that n-3 polyunsaturated fatty acids may act as activators of the Nrf2 antioxidant pathway. The antioxidant response, in turn, promotes neuronal differentiation and neurite outgrowth. Nrf2 has recently been suggested to be a cell intrinsic mediator of docosohexanoic acid (DHA) sign...

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Detalles Bibliográficos
Autores principales: Drolet, Jennifer, Buchner-Duby, Brodie, Stykel, Morgan G., Coackley, Carla, Kang, Jing X., Ma, David W. L., Ryan, Scott D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8101469/
https://www.ncbi.nlm.nih.gov/pubmed/33502893
http://dx.doi.org/10.1091/mbc.E20-09-0599

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