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Modeling the evolution of COVID-19 via compartmental and particle-based approaches: Application to the Cyprus case

We present two different approaches for modeling the spread of the COVID-19 pandemic. Both approaches are based on the population classes susceptible, exposed, infectious, quarantined, and recovered and allow for an arbitrary number of subgroups with different infection rates and different levels of...

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Autores principales: Alexandrou, Constantia, Harmandaris, Vangelis, Irakleous, Anastasios, Koutsou, Giannis, Savva, Nikos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8101925/
https://www.ncbi.nlm.nih.gov/pubmed/33956838
http://dx.doi.org/10.1371/journal.pone.0250709
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author Alexandrou, Constantia
Harmandaris, Vangelis
Irakleous, Anastasios
Koutsou, Giannis
Savva, Nikos
author_facet Alexandrou, Constantia
Harmandaris, Vangelis
Irakleous, Anastasios
Koutsou, Giannis
Savva, Nikos
author_sort Alexandrou, Constantia
collection PubMed
description We present two different approaches for modeling the spread of the COVID-19 pandemic. Both approaches are based on the population classes susceptible, exposed, infectious, quarantined, and recovered and allow for an arbitrary number of subgroups with different infection rates and different levels of testing. The first model is derived from a set of ordinary differential equations that incorporates the rates at which population transitions take place among classes. The other is a particle model, which is a specific case of crowd simulation model, in which the disease is transmitted through particle collisions and infection rates are varied by adjusting the particle velocities. The parameters of these two models are tuned using information on COVID-19 from the literature and country-specific data, including the effect of restrictions as they were imposed and lifted. We demonstrate the applicability of both models using data from Cyprus, for which we find that both models yield very similar results, giving confidence in the predictions.
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spelling pubmed-81019252021-05-17 Modeling the evolution of COVID-19 via compartmental and particle-based approaches: Application to the Cyprus case Alexandrou, Constantia Harmandaris, Vangelis Irakleous, Anastasios Koutsou, Giannis Savva, Nikos PLoS One Research Article We present two different approaches for modeling the spread of the COVID-19 pandemic. Both approaches are based on the population classes susceptible, exposed, infectious, quarantined, and recovered and allow for an arbitrary number of subgroups with different infection rates and different levels of testing. The first model is derived from a set of ordinary differential equations that incorporates the rates at which population transitions take place among classes. The other is a particle model, which is a specific case of crowd simulation model, in which the disease is transmitted through particle collisions and infection rates are varied by adjusting the particle velocities. The parameters of these two models are tuned using information on COVID-19 from the literature and country-specific data, including the effect of restrictions as they were imposed and lifted. We demonstrate the applicability of both models using data from Cyprus, for which we find that both models yield very similar results, giving confidence in the predictions. Public Library of Science 2021-05-06 /pmc/articles/PMC8101925/ /pubmed/33956838 http://dx.doi.org/10.1371/journal.pone.0250709 Text en © 2021 Alexandrou et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Alexandrou, Constantia
Harmandaris, Vangelis
Irakleous, Anastasios
Koutsou, Giannis
Savva, Nikos
Modeling the evolution of COVID-19 via compartmental and particle-based approaches: Application to the Cyprus case
title Modeling the evolution of COVID-19 via compartmental and particle-based approaches: Application to the Cyprus case
title_full Modeling the evolution of COVID-19 via compartmental and particle-based approaches: Application to the Cyprus case
title_fullStr Modeling the evolution of COVID-19 via compartmental and particle-based approaches: Application to the Cyprus case
title_full_unstemmed Modeling the evolution of COVID-19 via compartmental and particle-based approaches: Application to the Cyprus case
title_short Modeling the evolution of COVID-19 via compartmental and particle-based approaches: Application to the Cyprus case
title_sort modeling the evolution of covid-19 via compartmental and particle-based approaches: application to the cyprus case
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8101925/
https://www.ncbi.nlm.nih.gov/pubmed/33956838
http://dx.doi.org/10.1371/journal.pone.0250709
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