The first few days of a SARS-CoV-2 infection viewed at single-cell resolution

What transpires soon after inhaling Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the respiratory virus causing Coronavirus Disease 2019 (COVID-19)? Where does infection begin? What are the features of subsequent virus spread? How might host responses quickly contain infection? Two r...

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Detalles Bibliográficos
Autores principales: Gallagher, Tom, McCray, Paul B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Primer
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8101996/
https://www.ncbi.nlm.nih.gov/pubmed/33901166
http://dx.doi.org/10.1371/journal.pbio.3001217
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author Gallagher, Tom
McCray, Paul B.
author_facet Gallagher, Tom
McCray, Paul B.
author_sort Gallagher, Tom
collection PubMed
description What transpires soon after inhaling Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the respiratory virus causing Coronavirus Disease 2019 (COVID-19)? Where does infection begin? What are the features of subsequent virus spread? How might host responses quickly contain infection? Two recently published manuscripts have evaluated infection in primary cultures of well-differentiated cells to address these questions and bring more light on the proviral and antiviral components operating during the initial days after SARS-CoV-2 exposure.
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spelling pubmed-81019962021-05-17 The first few days of a SARS-CoV-2 infection viewed at single-cell resolution Gallagher, Tom McCray, Paul B. PLoS Biol Primer What transpires soon after inhaling Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the respiratory virus causing Coronavirus Disease 2019 (COVID-19)? Where does infection begin? What are the features of subsequent virus spread? How might host responses quickly contain infection? Two recently published manuscripts have evaluated infection in primary cultures of well-differentiated cells to address these questions and bring more light on the proviral and antiviral components operating during the initial days after SARS-CoV-2 exposure. Public Library of Science 2021-04-26 /pmc/articles/PMC8101996/ /pubmed/33901166 http://dx.doi.org/10.1371/journal.pbio.3001217 Text en © 2021 Gallagher, McCray https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Primer
Gallagher, Tom
McCray, Paul B.
The first few days of a SARS-CoV-2 infection viewed at single-cell resolution
title The first few days of a SARS-CoV-2 infection viewed at single-cell resolution
title_full The first few days of a SARS-CoV-2 infection viewed at single-cell resolution
title_fullStr The first few days of a SARS-CoV-2 infection viewed at single-cell resolution
title_full_unstemmed The first few days of a SARS-CoV-2 infection viewed at single-cell resolution
title_short The first few days of a SARS-CoV-2 infection viewed at single-cell resolution
title_sort first few days of a sars-cov-2 infection viewed at single-cell resolution
topic Primer
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8101996/
https://www.ncbi.nlm.nih.gov/pubmed/33901166
http://dx.doi.org/10.1371/journal.pbio.3001217
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